SUMMARY, EXPLANATION AND LIMITATIONS:
CD95, also known as Fas is a transmembrane glycoprotein, a member of nerve growth factor / tumor necrosis factor superfamily receptors. This surface molecule mediates the apoptotic process triggered by receptors. Fas antigen is expressed on the surface of several cell types including T and B lymphocytes and activated lymphoblastoid T cell lines.
Immunogen: Synthetic peptide derived from the C-terminus of human CD95.
Staining pattern: Cell membrane.
Positive control: Tissue sample from small intestine.
This antibody is designed for the specific localization of human CD95 using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.