SUMMARY, EXPLANATION AND LIMITATIONS:
CD23 is a 45 kDa glycoprotein, present in a subpopulation of a fresh separation of peripheral blood and tonsil B cells and strongly expressed in EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor in B cell. The expression of CD23 has been detected in neoplastic cells of chronic lymphocytic leukemia B-cell lymphoma and some cases of centroblastic / centrocytic.
Immunogen: Recombinant protein encoding human CD23 48-248aa.
Staining pattern: Cell membrane.
Positive control: Tissue sample from tonsil.
This antibody is designed for the specific localization of human CD23 using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.