SUMMARY, EXPLANATION AND LIMITATIONS:
CD20 is a 33 kDa surface antigen of leucocytes. It consists of four transmembrane regions and also of cytoplasmic N- and C-termini. CD20 is mainly expressed by B-cells but also by some normal and neoplastic T-cells.
Immunogen: Synthetic peptide corresponding to the C-terminus of humane CD20.
Staining pattern: Cell membrane.
Positive control: Tissue sample from tonsil or lymph node.
This antibody is designed for the specific localization of human CD20 using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.