SUMMARY, EXPLANATION AND LIMITATIONS:
Actin is an abundant cytoskeletal protein found in all cells. The protein’s 42 kD peptide chain assumes two physical forms: globular actin, which may serve as a cytoplasmic storage pool, and fibrous actin, which, in conjunction with myosin, generates muscle contraction. In non-muscle cells, actin appears to be involved in a variety of functions, such as cell motility, exocytosis, and phagocytosis.
Immunogen: N-Terminal decapeptide of alpha skeletal muscle isoform of actin.
Staining pattern: Cytoplasmic.
Positive control: Tissue sample from skeletal muscle.
This antibody is designed for the specific localization of human Actin, Skeletal Muscle using IHC techniques in formalin-fixed, paraffin-embedded tissue sections.